MONOVISC® is a treatment for the symptoms of osteoarthritis. It is a single, intra-articular injection made of ultra pure, high molecular weight sodium hyaluronate that is manufactured by bacterial fermentation. This viscoelastic supplement is indicated as a replacement for the synovial fluid in human joints, acting as a lubricant and mechanical support, and it can treat symptoms of osteoarthritis and other human joint conditions. Physicians commonly use an 18-21 gauge needle to inject MONOVISC® into the knee, but the physician will determine the final needle selection based on the individual patient's needs. MONOVISC® is meant for use on one patient only and should never be re-sterilized.