ELLANSЀ™ E is an implant composed of a gel carrier of phosphate buffered saline (PhEur), glycerin (PhEur), and carboxymethylcellulose (USP) that contains synthetic Poly-e-Caprolaction (PCL) microspheres. This soft medical polymer is completely bioresorbable, non-permanent, non-pyrogenic, sterile, and latex-free. PCL is a well-known bioresorbable product approved by the Food and Drug Administration (FDA) and CE-marked for many commercial applications. Doctors have used PCL for decades and it has a good safety record. With a particle size of 25-50 microns, ELLANSЀ™ E should be injected using a 27 gauge needle to correct wrinkles and restore volume to skin.