DUROLANE® is an intra-articular injection to treat symptoms of mild to moderate knee or hip osteoarthritis. The 3ml glass syringe contains a sterile, transparent, viscoelastic gel with 20mg/ml of stabilized non-animal hyaluronic acid in a buffered sodium chloride solution that has a pH of 7. Indications of DUROLANE® include treatment of mild to moderate osteoarthritis symptoms in certain synovial joints as well as treatment of pain after arthroscopic procedures. The recommended DUROLANE® dose is 1ml per knee, shoulder, or hip joint or 1-2ml per elbow, ankle or other intermediate joint, or approximately 1ml per thumb or other small synovial joint. DUROLANE® is a single dose, single injection preparation, and physicians should only inject DUROLANE® once per treatment course. Only an authorized physician, or other person as authorized by local legislation, should inject DUROLANE®.